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Intervention: Clostridium difficile vaccine

Found 22 matching trials

Safety and Immunogenicity Study of GSK's Clostridium Difficile Vaccine 2904545A When Administered in Healthy Adults Aged 18-45 Years and 50-70 Years

PHASE1

The purpose of this study is to generate safety, reactogenicity (assessment...

Status

Completed

Location

GSK Investigational Site

Start Date

2019-08-05

Trial ID

NCT04026009

Treatments Being Tested

C. difficile investigational vaccine based on the F2 antigen (GSK2904545A)C. difficile investigational vaccine based on the F2 antigen (GSK2904545A) adjuvanted with AS01B Placebo

Safety, Tolerability, and Immunogenicity Study of a Clostridium Difficile Toxoid Vaccine in Healthy Adult Volunteers

PHASE1

The purpose of this study is to determine the safety and tolerability of a ...

Status

Completed

Location

Multiple Locations

Start Date

2005-07

Trial ID

NCT00127803

Treatments Being Tested

Placebo (vaccine diluent)Clostridium difficile vaccine Clostridium difficile vaccine Clostridium difficile vaccine

Study of a Clostridium Difficile Toxoid Vaccine (ACAM-CDIFF™) in Subjects With Clostridium Difficile Infection

PHASE2

Primary objective: To compare the event rate of CDI in groups assigned to A...

Status

Completed

Location

Multiple Locations

Start Date

2009-02

Trial ID

NCT00772343

Treatments Being Tested

0.9% Normal Saline Clostridium difficile toxoid vaccine Clostridium difficile toxoid vaccine with adjuvant Clostridium difficile toxoid vaccine

Clostridium Difficile Vaccine Safety, Tolerability, and Immunogenicity Study in Japanese Adults

PHASE1

The first-in-Japanese study B5091010 has been designed to evaluate the safe...

Status

Completed

Location

SOUSEIKAI Sumida Hospital (formerly Medical Co. LTA Sumida Hospital)

Start Date

2016-02

Trial ID

NCT02725437

Treatments Being Tested

Clostridium difficile Vaccine Placebo

Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults

PHASE2

This study will further evaluate the ACAM-CDIFF™ vaccine in a population of...

Status

Completed

Location

Multiple Locations

Start Date

2010-10

Trial ID

NCT01230957

Treatments Being Tested

Clostridium difficile toxoids A and B (Low-dose with adjuvant)Clostridium difficile toxoids A and B (Low-dose without adjuvant)Clostridium difficile toxoids A and B (high-dose with adjuvant)Clostridium difficile toxoids A and B (high-dose without adjuvant)Placebo: 0.9% normal saline Clostridium difficile toxoids A and B (high-dose with adjuvant)Clostridium difficile toxoids A and B (high-dose with adjuvant)

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

PHASE3

The purpose of the study is to learn about how effective, safe, and tolerab...

Status

Recruiting

Location

North Alabama Research Center

Start Date

2025-12-10

Trial ID

NCT07282665

Treatments Being Tested

C.difficile vaccine Saline Placebo

Study of a Candidate Clostridium Difficile Toxoid Vaccine in Healthy Adult Subjects Aged 40 to 75 Years in Japan

PHASE1

The aim of the study is to evaluate a candidate C. difficile Toxoid Vaccine...

Status

Completed

Location

Multiple Locations

Start Date

2013-07

Trial ID

NCT01896830

Treatments Being Tested

Clostridium difficile Toxoid Vaccine 0.9% normal saline

A Study To Investigate Two 3-dose Schedules Of A Clostridium Difficile Vaccine In Healthy Adults Aged 65 to 85 Years

PHASE2

This study will investigate a Clostridium difficile vaccine in healthy adul...

Status

Completed

Location

Avail Clinical Research, LLC

Start Date

2015-07-16

Trial ID

NCT02561195

Treatments Being Tested

Clostridium difficile Vaccine Placebo

A Study To Investigate A Clostridium Difficile Vaccine In Healthy Adults Aged 50 to 85 Years, Who Will Each Receive 3 Doses Of Vaccine.

PHASE2

This study will investigate a Clostridium difficile vaccine in healthy adul...

Status

Completed

Location

Avail Clinical Research, LLC

Start Date

2014-07

Trial ID

NCT02117570

Treatments Being Tested

Clostridium difficile vaccine Clostridium difficile vaccine Placebo

An Open-label Study Assessing Safety, Immunogenicity and Dose Response of IC84

PHASE1

An open-label Phase 1 Study Assessing the Safety, Immunogenicity and Dose R...

Status

Completed

Location

Privatklinik Leech

Start Date

2010-12

Trial ID

NCT01296386

Treatments Being Tested

IC84

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